伊利诺伊大学芝加哥分校研究出分离循环肿瘤细胞的新系统

概述：目前，一种新型多流微流体系统被研发出来，可用于分离患有非小细胞肺癌（NSCLC）患者体内的循环肿瘤细胞（CTC）。

非小细胞肺癌（NSCLC）约占所有肺癌的85％。 循环肿瘤细胞（CTC）是从原发性肿瘤释放出并通过血液在体内运输的细胞。这些细胞携带的信息对于精确的癌症检测、监测和治疗至关重要。然而，迄今为止一直缺乏用于分离CTC的高质量方法。伊利诺伊大学芝加哥分校Ian Papautsky的研究小组开发了一种新型多流微流体器件，该器件可从NSCLC患者的血液中分离出CTC，并且具有很高的可信度。研究者认为，他们的多功能器件在从NSCLC和其他癌症患者的CTC提取信息上具有相当大的潜力。

A novel multi-flow microfluidic system has been devised to isolate circulating tumor cells (CTCs) in patients with non-small cell lung cancer (NSCLC). NSCLC accounts for around 85% of all lung cancers. CTCs are cells that have been released from a primary tumor and are transported around the body by the blood. Those cells carry information that is critical for precise cancer detection, monitoring, and treatment; however, a high-quality method for isolating CTCs has hitherto been lacking. A team headed by Ian Papautsky at the University of Illinois at Chicago developed a novel multi-flow microfluidic device that affords high fidelity in separating CTCs from the blood of NSCLC patients. The authors believe that their versatile device offers considerable potential for facilitating extraction of information from CTCs in NSCLC and other forms of cancer.