大家好,下面为大家总结了近期液体活检/精准医疗领域的研究进展,该列表相关进展影响因子较小,但仍可起到抛砖引玉的作用,提供给我们研究和应用线索和启示。
1、循环肿瘤细胞(CTC)
卵巢癌临床研究:Immunobiochemical pathways of neopterinformation and tryptophan breakdown via indoleamine 2,3-dioxygenase correlatewith circulating tumor cells in ovarian cancer patients- A study of the OVCADconsortium. by Johanna M Gostner, Eva Obermayr, …,Robert Zeillinger (2018) Gynecol. Oncol. (impact factor: 5)
膀胱癌综述:Circulating tumor cells in bladder cancer:Emerging technologies and clinical implications foreseeing precision oncology. by Rita Azevedo, Janine Soares, …, José Alexandre Ferreira (2018)Urol. Oncol. (impact factor: 3.8)
2、循环肿瘤DNA(ctDNA)
乳腺癌内分泌治疗:High-sensitivity assay for monitoring ESR1mutations in circulating cell-free DNA of breast cancer patients receivingendocrine therapy. by Laura Lupini, Anna Moretti,…, Massimo Negrini (2018) Sci Rep (impact factor: 4.3)
ctDNA技术方法:Mutation detection using plasma circulatingtumor DNA (ctDNA) in a cohort of asymptomatic adults at increased risk forcancer. by Anja Kammesheidt, Theresa R Tonozzi,Stephen W Lim, Glenn D Braunstein (2018) International journal of molecularepidemiology and genetics
结直肠癌研究:Monitoring the effect of first line treatmentin RAS/RAF mutated metastatic colorectal cancer by serial analysis of tumorspecific DNA in plasma. by C B Thomsen, T F Hansen,…, A Jakobsen (2018) Journal of experimental & clinical cancer research :CR
3、精准医疗领域研究进展
肿瘤突变功能注释:Systematic Functional Annotation of SomaticMutations in Cancer. by Patrick Kwok-Shing Ng, JunLi, …, Gordon B Mills (2018) Cancer Cell (impact factor: 27.4)
Activation of AMPK by simvastatin inhibited breast tumorangiogenesis via impeding HIF-1α-induced pro-angiogenic factor. by Ji-Chang Wang, Xiong-Xiong Li, …, Pei-Jun Liu (2018) Cancer Sci.(impact factor: 4)
早期肿瘤预测复发:Predictors of recurrence and survival ofpathological T1N0M0 invasive adenocarcinoma following lobectomy. by Yiyang Wang, Difan Zheng, …, Haiquan Chen (2018) J. Cancer Res.Clin. Oncol. (impact factor: 3.5)
4、外泌体研究进展
外泌体在前列腺癌中研究:Exosomal αvβ6 integrin is required formonocyte M2 polarization in prostate cancer. byHuimin Lu, Nicholas Bowler, …, Lucia R Languino (2018) Matrix Biol. (impactfactor: 7.4)
外泌体在早期非小肺癌中的复发检测:Usefulness of Plasma Exosomal MicroRNA-451a asa Noninvasive Biomarker for Early Prediction of Recurrence and Prognosis ofNon-Small Cell Lung Cancer. by Rie Kanaoka, HisaeIinuma, …, Masafumi Kawamura (2018) Oncology (impact factor: 2.3)
外泌体在肝癌多药耐药方面的研究:Exosomal microRNA-32-5p induces multidrugresistance in hepatocellular carcinoma via the PI3K/Akt pathway. by Xiao Fu, Mengjie Liu, …, Tao Tian (2018) Journal of experimental& clinical cancer research : CR |